Nutrient absorption in the intestine
Masters Project
![Generated image of intestines and stomach](/content/auckland/en/abi/study-with-us/study-options/research-projects/abi-research-project-22/_jcr_content/leftpar/imagecomponent/image.img.480.low.jpg/1714530725274.jpg)
The villus is the structural and functional unit of the intestine involved in nutrient absorption, luminal sensing, satiety signaling and immune activity. This project aims to develop a biophysical model of nutrient absorption and mechanosensing in the villus. A three-dimensional structural model of the villus incorporating cell layers and blood vessel network will be developed using micro-CT imaging. Proteins involved in nutrient absorption and mechanosensing will be identified using proteomic methods. Existing mathematical models of the relevant proteins will be embedded into the structural model to create a biophysical model of nutrient absorption and transport. The project will support the ABI's efforts to develop digital twins of whole-body nutrient/energy homeostasis.
Desired skills
- A background in engineering, biology or physiology.
Funding
12 Labours
Contact and supervisors
Contact/Main supervisor
Supporting supervisor(s)
- Peng Du
- Hayley Reynolds
Page expires: 1 September 2024