Nutrient absorption in the intestine

Masters Project

Generated image of intestines and stomach

The villus is the structural and functional unit of the intestine involved in nutrient absorption, luminal sensing, satiety signaling and immune activity. This project aims to develop a biophysical model of nutrient absorption and mechanosensing in the villus. A three-dimensional structural model of the villus incorporating cell layers and blood vessel network will be developed using micro-CT imaging. Proteins involved in nutrient absorption and mechanosensing will be identified using proteomic methods. Existing mathematical models of the relevant proteins will be embedded into the structural model to create a biophysical model of nutrient absorption and transport. The project will support the ABI's efforts to develop digital twins of whole-body nutrient/energy homeostasis.

Desired skills

A background in engineering, biology or physiology.

Funding

12 Labours

Contact and supervisors

For more information or to apply for this project, please follow the link to the supervisor below:

Contact/Main supervisor

Vinod Suresh

Supporting supervisor(s)

Peng Du
Hayley Reynolds