Which babies are at increased risk of adverse long-term outcomes as a result of neonatal hypoglycaemia?

Question 28

PICO (Population, Intervention, Comparison, Outcome): Should risk factors for adverse long-term outcomes vs. no risk factors for adverse long-term outcomes be used for guiding management of babies at risk of neonatal hypoglycaemia?

Recommendation

No recommendation made.

Justifications

In the follow-up of the hPOD trial, associations between neonatal hypoglycaemia and neurodevelopmental problems at 2 years were identified in children whose mothers had diabetes, but it was not possible to analyse outcomes separately for other risk groups.

Implementation considerations

Nil.

Monitoring and evaluation

Nil.

Research priorities

Studies are needed on:

  • The long-term outcomes of neonatal hypoglycaemia for individual risk groups, and the effects of treatments of neonatal hypoglycaemia on these.

Health equity

There are no data about whether Māori or other groups are at increased risk of adverse long-term outcomes after neonatal hypoglycaemia, so the effect on health equity is unknown.